Genetic Variation, Natural Selection, and Evolution


  • Megan Morgan Hoffman Berea College


This Learning Cycle activity is designed for an introductory college biology course, in a section on population genetics and evolution. Evolution is a cornerstone of the Biological Sciences. Genetic variation within a population can be acted upon by agents of natural selection, leading to evolution. This activity provides an opportunity to explore the relationships among genetic variation, natural selection, and the evolution of a population.  After successfully completing this activity, students will be able to: explain why it is difficult for agents of natural selection to remove recessive alleles from a population's gene pool; articulate the roles of genetic variability and natural selection on evolutionary outcomes; form an argument or reach a conclusion supported with evidence by evaluating, analyzing, and/or synthesizing relevant information.


Level: Undergraduate
Setting: Classroom
Type: Learning Cycle
Discipline: Biology
Course: Introductory Biology
Keywords:  alleles, genotype, phenotype, genetic variation, natural selection, evolution

ToC Image: Rabbits with Brown and White Phenotypes




How to Cite

Hoffman, M. M. (2024). Genetic Variation, Natural Selection, and Evolution. POGIL Activity Clearinghouse, 4(2). Retrieved from



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